2024 Brn3a是什么

Brn3a是什么

Author: ahrz

August undefined, 2024

Web7 rows · BRN3A (POU4F1) is a class IV POU domain-containing transcription factor highly expressed in the developing sensory nervous system and in cells of the B- … WebNov 11, 2009 · Electroporation in utero. Timed-pregnant ICR mice (Charles River) bearing E13.5 embryos were anesthetized by isoflurane inhalation, their abdominal cavity was incised, and the uterine horns were exposed as described by Saito (2006).Approximately 1 μl of solution encoding Brn3a and/or green fluorescent protein (GFP) was injected into …

Brn3a - Synaptic Systems

WebMar 7, 2014 · Methods and Findings. We generated conditional Cre knock-in alleles at the Brn3a and Brn3b loci, Brn3a CKOCre and Brn3b CKOCre.When crossed to mice expressing the Dre recombinase, the endogenous Brn3 gene expressed by Brn3a CKOCre or Brn3b CKOCre is removed and replaced with a Cre recombinase, generating Brn3a … WebBrn-3a Antibody (14A6) is an IgG 2b κ mouse monoclonal Brn-3a antibody (also designated BRN3A antibody, POU4F1 antibody, or POU class 4 homeobox 1 antibody) suitable for … jewelry stores peterborough ontario

Brn3a - Synaptic Systems

WebBrn-3a Antibody (14A6) is an IgG 2b κ mouse monoclonal Brn-3a antibody (also designated BRN3A antibody, POU4F1 antibody, or POU class 4 homeobox 1 antibody) suitable for … WebAll lanes : Anti-BRN3A antibody [EP1972Y] (ab81213) at 1/2000 dilution (purified) Lane 1 : SW480 (Human colorectal adenocarcinoma epithelial cell) whole cell lysates Lane 2 : Mouse cerebellum lysates Lane 3 : Rat brain … WebEntrez Gene Number. NM_006237.3. Entrez Gene Summary. BRN3A (POU4F1) is a class IV POU domain-containing transcription factor highly expressed in the developing sensory nervous system and in cells of the B- and T-lymphocytic lineages (Gerrero et al., 1993 [PubMed 8248179]). [supplied by OMIM] Gene Symbol. POU4F1. instalar directv go en amazon fire stick

Brn3a is a transcriptional regulator of soma size, target field ...

POU4F1 - Wikipedia

WebDec 14, 2005 · Materials and Methods. Generation of mutant mice. The mice carrying a null allele of Brn3a used in the present study have been described previously (Xiang et al., 1996; Eng et al., 2001).Transgenic … WebJan 15, 2002 · In mice, Brn3 POU domain transcription factors play essential roles in the differentiation and survival of projection neurons within the retina, inner ear, dorsal root and trigeminal ganglia. During retinal ganglion cell differentiation, Brn3b is expressed first, followed by Brn3a and Brn3c. Targeted deletion of Brn3b, but not Brn3a or Brn3c, leads … jewelry stores perth waWebSep 1, 2024 · These results imply that Brn3a suppresses tumor metastasis via c-MET/STAT3 inhibition and EMT suppression in thyroid cancer. Conclusions: Our findings show that Brn3a is a potential tumor suppressor that leads to reduced cancer cell migration and invasion in thyroid cancer. Elucidation of the Brn3a-regulated cancer pathways may … jewelry stores perkins cove maine

"WebMay 2, 2024 · We have induced retina-specific Cre recombination of our conditional knock-in reporter alleles at the Pou4f1 (Brn3a CKOAP) and Pou4f2 (Brn3b CKOAP) loci using the Pax6α:Cre driver ().When the sister chromosome carries a conventional KO allele, recombination of the conditional allele results in cells lacking both copies of the … " - Brn3a是什么

Brn3a是什么

Brn-3a/BRN3A/POU4F1 Antibody (14A6) SCBT

WebSummary. 胶质细胞转换为特定的神经元是一种潜在的神经退行性疾病和脑损伤等的潜在治疗方式。. 但存在转换效率低、无法在体内产生所需的神经元类型等限制性因素。. 作者使 … WebMay 27, 2024 · 关注. 据我个人之见，小RNA的“小”这个字的初衷就在于表示它只由较少的核苷酸组成（一个说法是40-500nt），分子量比较小，最早是在大肠杆菌发现的 (Hindley, …

Did you know?

WebJun 29, 2024 · Background About 20–30 distinct Retinal Ganglion Cell (RGC) types transmit visual information from the retina to the brain. The developmental mechanisms by which RGCs are specified are still largely unknown. Brn3a is a member of the Brn3/Pou4f transcription factor family, which contains key regulators of RGC postmitotic … WebBrn-3a Antibody (14A6) is an IgG 2b κ mouse monoclonal Brn-3a antibody (also designated BRN3A antibody, POU4F1 antibody, or POU class 4 homeobox 1 antibody) suitable for the detection of the Brn-3a protein of …

WebOct 8, 2013 · Previously, we described cell autonomous effects of Brn3b (Pou4f2) and Brn3a (Pou4f1) on RGC axon and dendrites development. Methods and Findings We now have investigated genetic interactions between Brn3 transcription factors with respect to RGC development, by crossing conventional knock-out alleles of each Brn3 gene with … http://www.biodog.cn/index/InformationRow?id=403

WebMay 18, 2024 · As6Brn-3a is an endogenous marker of RGCs .Key wordsretinal ganglion cells; Thy-1.1; Brn-3a; immunohistochemistry7前言青光眼是一类以特征性视野缺损和视 … WebMar 26, 2009 · In the experiments described below, we used either of two heterozygous configurations at the Brn3a or Brn3b loci: the conditional allele over the WT allele (e.g., Brn3b CKOAP/+) or the conditional allele over a conventional null allele (e.g., Brn3b CKOAP/−).In the former case, Cre-mediated recombination results in AP expression in …

WebJan 18, 2012 · The three members of the Brn3 family of POU-domain transcription factors (Brn3a/Pou4f1, Brn3b/Pou4f2, and Brn3c/Pou4f3) are expressed in overlapping subsets of visual, auditory/vestibular, and somatosensory neurons. Using unmarked Brn3-null alleles and Brn3 conditional alleles in which gene loss is coupled to expression of an alkaline ...

WebTarget Information. BRN3A is a class IV POU domain-containing transcription factor highly expressed in the developing sensory nervous system and in cells of the B- and T-lymphocytic lineages. For Research … jewelry stores philadelphia chestnut streetWebBrn3a, also referred to as POU4F1, RGC-1 or Oct-T1, is a transcription factor highly expressed in the developing peripheral sensory nervous system, cells of the B- and T … jewelry stores port of spainWebNov 29, 2011 · At E11.5, Brn3a and Brn3b were expressed in dA2 and dA4 neurons, whereas Brn3a alone was expressed in dA1 neurons (Fig. 4 D and E). The dA3 neurons had a unique status in that expression of Brn3a was fleeting and weak, soon extinguished along the ventral migration route (Fig. 4 D and D Inset) and that of Brn3b was … jewelry stores peterborough mallWebJun 9, 2024 · Knockout of Brn3a upregulated Brn3b expression, which increased expression of the Brn3b target genes cyclin D1 (CCND1; 168461) and Bax , resulting in cardiomyocyte apoptosis and heart morphologic defects that likely caused death of Brn3a -/- mice soon after birth. Brn3a -/- and Brn3b -/- double-knockout mice suffered early … jewelry stores port clinton ohioWebRNA干扰（RNA interference，RNAi）是指在进化过程中高度保守的、由双链RNA（double-stranded RNA，dsRNA）诱发的、同源mRNA高效特异性降解的现象。基因沉默，主要有 … instalar dlc the sims 4 instalar dispositivo sonido windows 10Web在这里，小编想和大家分享一些常见的神经元和神经胶质细胞标记物。. 1. 神经元特异性烯醇化酶（NSE）. 1) 广泛使用的神经元标记物。. 2) NSE是一种参与糖酵解途径的烯醇化 … instalar device manager